remission Archives - Page 2 of 2 - Unhinged

Unhinged Episode #027: Electric Avenue

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Unhinged Episode #027: Electric Avenue

In this episode, we catch up with Doug’s progress with his DBS. Still going strong, even after a stressful few days. The neurological corrections (based on MEG brain imaging) are still in place and seem to still be working their magic a full month after altering the DBS settings.

Deep Brain Stimulation has already helped patients with Parkinson’s disease as well as dystonia. We play a couple of excerpts from Dr. Andres Lozano’s TED talk where he shows in real time how switching the DBS on totally stops a Parkinson’s patient from shaking, and essentially cures a child from severe dystonia. Tapping into the brain and sending an electric charge into very specific regions can kickstart malfunctioning neurons and bring hope to those who suffer from all sorts of mental illnesses.

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DBS helps a Parkinson’s patient


DBS helps a patient with dystonia
 
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Unhinged Episode #024: Happy Days

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Unhinged Episode #024: Happy Days

Doug’s new setting on his DBS seems to still be working its miracles. Since the MEG scan pointed to three settings that showed promising neural activity, Doug has been on the first setting, and so far so good! No more shooting blind… with brain imaging, we now have a more reliable method of determining effective treatment.

We’re cautiously optimistic about this, and really hope it lasts into full remission, unlike the roller coaster setting he had previously. The best part of it all is that he now not only has hope, but is looking forward to a more “normal” future.

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Unhinged Episode #019: A New Hope

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Unhinged Episode #019: A New Hope

After a long three weeks of relapse, Doug is finally starting to emerge from the darkness. In this episode, Doug recalls some of what he was feeling during that time… the anger, the frustration, the hopelessness. We also respond to a couple of emails we received about Episode #18: Relapse Part 2 – The Call. Apparently, the frankness and reality of our last episode struck a chord with some listeners in a good way. Hearing that our show has actually helped anyone is a huge validation of everything we’re trying to do. Thank you!

Lastly, we talk about Doug’s recent magnetoencephalography (MEG) session, where multiple settings were dialed in on his DBS, then his brain scanned. Being able to image his brain activity with differing DBS settings should hopefully provide some insight into what exactly the DBS is doing and how his brain is reacting. Now we wait for the analysis of his results.

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Unhinged Episode #016: Mission Remission

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Unhinged Episode #016: Mission Remission

NOTE: This podcast was recorded on July 3rd and deals with Doug’s recent 2-month remission. However, as of July 4th, Doug’s mood has taken a downward turn, so the declaration of a full remission was a bit premature. We will have more information about this on next week’s show, so please stay tuned. In the meantime, please enjoy episode #16.

This week’s episode deals with Doug’s recent two-month remission. Technically, a two-month period with no major depressive symptoms is considered a full remission. This is where he is right now, but how long will it last?

We also learn about the true origins of Doug’s mental illness. There is now scientific proof that his genetics have a great deal to do with his treatment-resistant depression. The good news is that a DNA profile, combined with advanced brain imaging techniques, helps doctors more accurately try different therapies and medications that are better targeted at an individual. This should help usher out the era of stab-in-the-dark medicine, and begin a new era of targeted, customized, and more effective treatments.

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